What causes peripheral artery disease?
Atherosclerosis is the cause of PAD, which is a buildup of fats, cholesterol and other substances in and on the walls of the peripheral arteries (the arteries that carry blood to the legs and arms). Also known as plaque, these substances collect in the arteries and over time, can cause the blood vessels to narrow.
People who have a family history of PAD, diabetes, high blood pressure, high cholesterol, are overweight or over 50 years of age are at risk for atherosclerosis. Smoking is also a risk factor for PAD. Left untreated, PAD can lead to critical limb ischemia and a possible amputation. As plaque can also build up in other blood vessels within the body, the risk of stroke and heart attack is higher in those with PAD.
The ankle brachial index (ABI) test is performed at most doctor’s offices and is often the first test used to diagnose PAD. If further testing is needed, a duplex ultrasound, X-ray arteriogram, CT angiogram or MR angiogram may also be used.